By I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins
''...the quantity undoubtedly succeeds total as an in-depth survey of either the biology and the biochemistry of a ubiquitous and astonishingly assorted family members of very complicated enzymes. each team with an curiosity in those proteins may still personal a copy.'' -CELL (July 2003) ''The editors of ABC Proteins: From micro organism to Man have valiantly tried to surround during this quantity the total scope of analysis on those proteins, from atomic-resolution constitution to human genetic illnesses, and from Escherichia coli to Homo sapiens and Arabidopsis thaliana... What the e-book makes noticeable is that almost all ABC proteins are membrane localized, ATP established, basic energetic transporters...In addition to advances in our realizing of ABC transporter constitution, a number of chapters within the ebook additionally describe growth that has been made in elcuidating the mechanisms of delivery. the amount absolutely succeeds total as an in-depth survey of either the biology and the biochemistry of a ubiquitous and astoundingly diversified relatives of very advanced enzymes. each staff with an curiosity in those proteins should still personal a duplicate. ultimately, this e-book makes a powerful case that many laboratories that will not but suspect it is going to quickly have a way more abiding curiosity in ABC proteins.'' ''...well equipped and incorporated superbly transparent colour photographs and figures.'' -E STREAMS (July 2003)
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Additional resources for ABC Proteins. From Bacteria to Man
176, 187–206. M. H. (1997) The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt’s disease (ABCR). FEBS Lett. 409, 247–252. , et al. (1998) Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain. J. Biol. Chem. 273, 32167–32175. , Wolfger, H. and Kuchler, K. (1999) Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochim. Biophys. Acta 1461, 217–236. P. and Trowsdale, J.
And Schuster, W. (1995) orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria. Mol. Gen. Genet. 246, 166–173. M. R. (1987) Cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium. J. Bacteriol. 169, 3189–3198. , Drobnik, W. and Schmitz, G. (2000) Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7). Biochem. Biophys. Res. Commun. 273, 532–538. , Trowsdale, J. J. (1999) Antigen presentation: TAP dances with ATP.
6B). The ABC proteins are related to those of the MOI family but no significant similarity could be detected between SSA proteins and BPs of BPD transporters. Some systems have been partially characterized. , 1999). , 1998). , 2001). Interestingly, the IM and the SSA proteins of an MKL family system in M. tuberculosis have been subjected to extensive gene duplications, so that eight genes for IMs and ten genes for SSA proteins were identified in the genome. , 1993). It is therefore tempting to speculate that MKL systems are implicated in the maintenance of bacterial outer cell surface integrity.
ABC Proteins. From Bacteria to Man by I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins